The invention relates to the field of food biotechnology and can be applied for production of fermented polyfunctional synbiotic beverages for mass consumption. There is proposed a microbial culture association that consists of individual cultures Lactobacillus plantarum LUMBI B78 and Saccharomyces cerevisiae LUMBI R42 in ratio 2:1 deposited in Latvian Culture Collection of Microorganisms under accession number P 1399. The association can be used for the production of fermented beverages.