A magnetic resonance imaging (MRI) system includes at least one controller configured to first acquire at least MRI locator image data for different portions of patient anatomy at each of different imaging stations for a defined multi-station locator sequence. An operator may interface with a respectively corresponding displayed locator image for each imaging station to set diagnostic scan sequence parameters for subsequent diagnostic MRI scans of corresponding portions of patient anatomy. Diagnostic MRI scan data is automatically acquired at each of the imaging stations in a multi-station diagnostic scan sequence that, if desired, can be seamlessly continued without operator interruption once begun.