Jordi ORTIZ SAGRISTA,Ramon BOSSER ARTAL,Laura MORENO MARTINEZ,Ana Cristina CALVO ROYO,Maria Jesus MUÑOZ GONZALVO,Pilar ZARAGOZA FERNANDEZ,Rosario OSTA PINZOLAS
申请号：
US15322777
公开号：
US20170151316A1
申请日:
2015.07.01
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to the use of the non-toxic proteolytic C fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition characterized, at least in part, by a decreased amount, development, or metabolic activity of muscle are provided. The disclosed compositions and method are also useful for the treatment of condition in which increase in muscle mass and muscle strength are desirable, including cosmetic uses.
