Segmentation is provided in multi-modal reconstruction of functional information. Rather than using HU values for segmentation, the HU values are converted into linear attenuation coefficients, such as in a μ-map (Mu map). The conversion uses different functions for different ranges of the HU values. Linear attenuation coefficients are less likely subject to variation by patient, protocol, or scanner. The resulting segmentation may be more consistent across various clinical settings, providing for more accurate multi-modal reconstruction.