Jonathan D. McCanless;Jon P. Moseley;Michael E. Carroll
发明人:
Jon P. Moseley,Michael E. Carroll,Jonathan D. McCanless
申请号：
US11624460
公开号：
US08685464B2
申请日:
2007.01.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition； ii) a monocalcium phosphate monohydrate powder； and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.
