Joy GHOSH,Michael ROGUSKA,Andrew Anh NGUYEN,Thomas PIETZONKA,Stephen Hedrick POOR,Matthias MACHACEK,Chad Eric BIGELOW
申请号：
US15315626
公开号：
US20170290876A1
申请日:
2015.06.24
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is based, in part, on the discovery of peptide tags that increase the half-life and/or mean residence time of proteins or nucleic acids in the eye. In certain aspects the invention peptide tags increase the half-life and/or mean residence time of antibodies and antigen binding fragments, therapeutic proteins, protein receptors, DARPins and/or aptamers in the eye.
