Brad L. Gower,Carlos H. Castaneda,Jae Han Park,Clifford J. Herman
申请号：
US13939357
公开号：
US20140017310A1
申请日:
2013.07.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present disclosure provides pharmaceutical compositions comprising at least one active pharmaceutical ingredient or a pharmaceutically acceptable salt thereof, at least one hydrophilic plastomer, optionally at least one hydrophilic elastomer, and at least one deliquescent plasticizer, wherein the pharmaceutical compositions provide extended release of the API and have abuse deterrent properties. Also provided are methods for preparing the pharmaceutical compositions in which the components of the composition are humidified such that the deliquescent plasticizer deliquesces, thereby plasticizing the hydrophilic polymers.
