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Octapeptide compounds derived from somatostatin and the therapeutic use thereof
专利权人:
Marie-Thérèse Paternostre;Jean-Christophe Cintrat;Céline Valery;Roland Cherif-Cheikh;Franck Artzner;Maarten Ijsselstijn;Stéphane Roux;Bernard Rousseau
发明人:
Marie-Thérèse Paternostre,Jean-Christophe Cintrat,Céline Valery,Stéphane Roux,Bernard Rousseau,Maarten Ijsselstijn,Roland Cherif-Cheikh,Franck Artzner
申请号:
US13121928
公开号:
US09382306B2
申请日:
2009.09.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to novel octapeptide compounds of general formula (I): H-2-Nal 1-cyclo(Cys2-Tyr3-AA4-Lys5-Val6-Cys7)-Thr8-NH2. Since these products have a good affinity for certain somatostatin receptor subtypes, they are particularly advantageous for treating pathological states or diseases in which one (or more) somatostatin receptor(s) is (are) involved. These compounds furthermore have physiochemical properties that make it possible to envisage them in diverse solutions for the formulation of medicaments, for example as a pharmaceutically acceptable carrier. The invention also relates to pharmaceutical compositions containing said products and to the use thereof for the preparation of a medicament.
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中国工程科技知识中心
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