PHILIPPE JABLONSKI,KENICHI KAWASAKI,HENNER KNUST,ANJA LIMBERG,MATTHIAS NETTEKOVEN,HASANE RATNI,CLAUS RIEMER,XIHAN WU
申请号：
BRPI0815674
公开号：
BRPI0815674A2
申请日:
2008.08.12
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention relates to a compound of general formula wherein Ar, R1, R2, R3, R4, n, o, p, s, X and are as defined herein or to a pharmaceutically active salt thereof, including all stereoisomeric forms, individual diastereoisomers and enantiomers of the compound of formula (I) as well as racemic and non-racemic mixtures thereof. The compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
