Peter Charles Leonard Beverley,Elma Zaven Tchilian
申请号:
US13879983
公开号:
US20130273093A1
申请日:
2011.10.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to a method for immunising a subject against Mycobacterium tuberculosis ox Mycobacterium bovis. The method comprises parenterally administering to the subject an immunologically effective amount of a first antigen from the Mycobacterium or a first polynucleotide encoding the first antigen and administering to the lung of the subject an immunologically effective amount of a second antigen from the Mycobacterium or a second polynucleotide encoding the second antigen. The two administration steps are carried out less than four weeks apart. The invention also relates to a kit for carrying out the method of the invention.