The present invention particularly relates to rebesetin or a functional variant or fragment thereof for use as an angiogenesis inhibitor in the treatment of angiogenic diseases such as ocular diseases, cancers or inflammatory diseases that include angiogenic elements. [Selection diagram] None本発明は、特に、血管新生要素を含む眼疾患、癌又は炎症性疾患等の血管新生疾患の治療において、血管新生阻害剤として用いるためのレベセチン又はその機能的変異体若しくは断片に関する。【選択図】なし