Lars Christian Biilmann Rønn,Ibrahim John Malik,Jeffrey b. Stavenhagen,Søren Christensen,Jan Egebjerg,Arnout Gerritsen,Edward Van Den Brink,Paul Parren,Rob De Jong
申请号:
US15743549
公开号:
US20180305455A1
申请日:
2016.07.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).