ANNA KOHLMANN,DAVID C. DALGARNO,FENG LI,JIWEI QI,JOSEPH M. GOZGIT,NICHOLAS E. BENCIVENGA,RANNY M. THOMAS,WEI-SHENG HUANG,WILLIAM C. SHAKESPEARE,XIAOTIAN ZHU,YIHAN WANG,YUN ZHANG
申请号:
BR112019012224
公开号:
BR112019012224A2
申请日:
2017.12.14
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The invention relates to c-kit inhibitors useful in the treatment of cancers and other serine-threonine kinase-mediated diseases, having the formula: (i), wherein a, l, r1, r2, r3, and n are described herein .a invenção refere-se a inibidores de c-kit úteis no tratamento de cânceres e outras doenças mediadas por serina-treonina quinase, tendo a fórmula: (i), onde a, l, r1, r2, r3, e n são descritos neste documento.