The present invention relates to a biopsy assembly (1), for obtaining a tissue sample. The assembly (1) comprises an elongated tube shaped sleeve (2), extending along a longitudinal axis A. The sleeve (2) comprises a first cutting edge arrangement (3) at a distal end (4) of said sleeve (2), said sleeve (2) being provided with an opening (5) at said distal end (4), wherein said opening(5) being in communication with a cavity (6) adapted to receive said tissue sample. The assembly (1) further comprises an elongated drill unit (7),adapted to be removably arranged in said sleeve (2), and extending along a longitudinal axis B, said elongated drill unit (7) comprising a second cutting arrangement (8) arranged at a distal tip (9) of said drill unit (7). The assembly (1) is adapted to be in a first state,during an insertion phase of said assembly (1), in which state said elongated drill unit (7) is arranged in said sleeve (2), and in a second state, during a tissue sampling phase, wherein said elongated drill unit (7) is removed from said sleeve (2). The assembly (1) comprises a fixation member (10), wherein said sleeve (2) and said drill unit (7) are fixated in relation to each other by said fixation member(10), such that in said first state, said first cutting arrangement (3) and said second cutting arrangement (8) are adapted to perform a cooperating cutting action, when said assembly (1) is rotated in a first direction (d).La présente invention concerne un ensemble de biopsie (1) permettant dobtenir un échantillon de tissus. Lensemble (1) selon linvention comprend un manchon (2) en forme de tube allongé, qui sétend le long dun axe longitudinal A. Le manchon (2) comprend un premier agencement à bord tranchant (3) au niveau dune extrémité distale (4) dudit manchon (2), ledit manchon (2) étant pourvu dune ouverture (5) au niveau de ladite extrémité distale (4), ladite ouverture (5) se trouvant en communication avec une cavité (6) adaptée à recevoir ledit échantillon de tis