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Therapeutic use of gelatin hydrogels with a gel-sol transition at body temperature
专利权人:
发明人:
申请号:
EP11183232.5
公开号:
EP2574349A1
申请日:
2011.09.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention regards the use of gelatin hydrogels that are solid at room temperature and melt or present a gel-sol transition at temperatures near the body temperature, so assuming a liquid state when put contact with body, implanted in the body or heated at temperatures compatible with the body.The gelatin-based hydrogels may contain biologically active agents and/or cells that after hydrogel melting or gel-sol transition, are fast released in situ, thus explicating the therapeutic and biological action.The gelatin-based hydrogels, containing or not containing biologically active agents, may be solid at the temperature of the skin (33°C) and melt when water or aqueous solution at a temperature compatible to the body is poured onto for an easy removal of the hydrogels.
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