THE CHILDREN'S HOSPITAL OF PHILADELPHIA;THE CHILDRENS HOSPITAL OF PHILADELPHIA
发明人:
LEVY, ROBERT J.,ALFERIEV, IVAN,STACHELEK, STANLEY,CONNOLLY, JEANNE M.,CHRISTIAN, ABIGAIL
申请号:
CA2841573
公开号:
CA2841573A1
申请日:
2012.07.11
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to oxidation resistant bioprosthetic tissues and oxidation resistant bioprosthetic heart valve leaflets. Also provided are methods for preparing the oxidation resistant bioprosthetic tissues and bioprosthetic heart valve leaflets, and methods for preventing oxidative degeneration in bioprosthetic tissues, comprising immobilizing covalently an effective amount of an antioxidant to the bioprosthetic tissue.