Ann Moriarty,Didier Leturcq,Juli Degraw,Karen Kabat Stegman,Wei-Xing Shi,Xilian Yue,Zeling Cai
申请号：
BRPI0720342
公开号：
BRPI0720342A2
申请日:
2007.10.04
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Methods of processing inactivated artificial antigen presenting cells (aAPCs) and artificial antigen presenting cells with specificity for selected antigenic peptides are described, including their generation and use in cell therapy compositions comprising activated cytotoxic T lymphocytes. Inactivated aAPCs are advantageously generated through crosslinking, such as via a photoreaction involving a psoralen derivative and UVA irradiation.
