REPAKULA SREENATH,NARISHETTY SUNIL THOMAS KUMAR,PRICE JEFFREY ELLIS
申请号：
NZ60145011
公开号：
NZ601450A
申请日:
2011.02.15
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a controlled-release veterinary composition in a form of an orally deliverable tablet comprising: (a) at least one antibacterial bioactive agent for veterinary use (b) a polymer having molecular weight from about 1,000,000 to about 9,000,000 daltons, or a polymer having a viscosity in a range of from about 80,000 to about 120,000 mPa.s, in an amount of about 5% to about 60% of the total weight of the tablet and (c) at least one disintegrant agent in an amount between about 10% to about 50% of the total weight of the tablet. Also disclosed is the use of the composition to manufacture a composition used in treating dogs for pain, soft-tissue infections such as worms, allergic reactions and seizures. Preferable bioactive agents are amoxicillin, tulathromycin, ceftiofur, lincomycin hydrochloride, spectinomycin, marbofloxacin, cefpodoxime, proxetil, clinafloxacin, amoxicillin trihydrate/clavulanate potassium, chloramphenicol, tetracycline, penicillin VK, cefadroxil, clindamycin, neomycin sulphate, methenamine mandelate, sulfamethizole, sulfachlorpyridazine. Preferred control release polymers are Hypromellose 2208 or high molecular weight (2,000,000 to 4,000,000 daltons) polyethylene oxides (Polyox WSR n-60).
