CHITOSAN NANOFIBER FOR ANIONIC PROTEIN DRUG DELIVERY, METHOD OF PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION FOR TRANSMUCOSAL ADMINISTRATION COMPRISING THE CHITOSAN NANOFIBER
Hyuk Sang YOO,Ji Suk CHOI,Younghee KIM,Jihyun KANG
申请号:
US14146252
公开号:
US20140242145A1
申请日:
2014.01.02
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A chitosan nanofiber for delivering an anionic protein drug, a method of preparing the same, and a pharmaceutical preparation for transmucosal administration including the chitosan nanofiber are provided. The chitosan nanofiber including an anionic protein drug in a core and chitosan in a shell is prepared by coaxial electrospinning an aqueous solution of the anionic protein drug through an inner nozzle and a solution of the chitosan or a chitosan derivative through an outer nozzle.