Matthew Burger,Zhi-Jie Ni,Sabina Pecchi,Gordana Ataliah,Sarah Bartulis,Kelly Frazier,Aaron Smith,Joelle Verhagen,Yanchen Zhang,Allan Wagman,Simon Ng,Keith Pfister,Daniel J. Poon,Alicia Louie,Teresa Pi
申请号：
US13471111
公开号：
US08563549B2
申请日:
2012.05.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.
