Perry Peters,David Furlano,Daun Bahr,Daniel Van Kammen,Mark Brann
申请号：
US14702313
公开号：
US20150231126A1
申请日:
2015.05.01
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Combinations of 5-HT2A inverse agonists or antagonists such as pimavanserin with antipsychotics such as risperidone are shown induce a rapid onset of antipsychotic action and increase the responders when compared to therapy with the antipsychotic alone. These effects can be achieved at a low dose of the antipsychotic, thereby reducing the incidence of side effects. The combinations are also effective at decreases the incidence of weight gain and increased glucose or prolactin levels caused by the antipsychotic.
