A method is disclosed for making a guidewire for an endovascular medical system for treating a clot located in a target vessel. The method can include forming a substantially planar distal end of the guidewire； cutting a predetermined shape into the distal end of the guidewire, wherein the distal end is wider than a remainder of the guidewire proximal thereof, and wherein the predetermined shape is configured to minimize the likelihood of the guidewire tip entering a perforating vessel when delivered through the neurovasculature or across the clot.
