Timothy F. Briggs;Jinbo Lee;Frank G. Favaloro, Jr.;Stephen P. Hale;Daniel Wang;Wei-Chuan Sun;Julian F. Bond;Benjamin Adam Seigal;Nicholas Terrett
发明人:
Jinbo Lee,Julian F. Bond,Nicholas Terrett,Frank G. Favaloro, Jr.,Daniel Wang,Timothy F. Briggs,Benjamin Adam Seigal,Wei-Chuan Sun,Stephen P. Hale
申请号：
US12544604
公开号：
US08338565B2
申请日:
2009.08.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.
