PROBLEM TO BE SOLVED: To provide an osteoblast differentiation promoter that can improve the balance of bone metabolism by promoting the differentiation of a bone cell, particularly an osteoprogenitor cell, and is easy to take continuously daily, and has no problem in safety and to provide a composition containing the differentiation promotor for the prevention of osteopenic disease or for the improvement of symptoms thereof.SOLUTION: The invention provides an osteoblast differentiation promoter containing a solvent extract of the flower of Prunus, and a composition containing the extract, as an active ingredient, for the prevention of osteopenic disease or the improvement of symptoms thereof.EFFECT: The extract of the flower of Prunus accelerates the activity of alkaline phosphatase (ALP) depending on a concentration, and promotes the differentiation of the osteoblast.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】骨細胞、特に骨前駆細胞の分化を促進させることで骨代謝のバランスを改善することでき、且つ、日常継続的に摂取しやすく、安全性にも心配が無い骨芽細胞分化促進剤、及び該分化促進剤を含有する骨減少性疾患の予防又は症状改善用の組成物の提供。【解決手段】サクラの花の溶媒抽出物を含有する骨芽細胞分化促進剤、及び該抽出物を有効成分とする骨減少性疾患の予防又は症状改善用組成物。【効果】サクラの花の抽出物は濃度依存的にアルカリフォスファターゼ(ALP)の活性を亢進し、骨芽細胞の分化を促進する。【選択図】なし
