PROBLEM TO BE SOLVED: To provide an exposure prevention box for preventing an operator from erroneously sticking a needle of a syringe to a hand and staining gloves with a medicine, an organic solvent, or the like when preparing an anticancer agent, the organic solvent, or the like in an open-type safety cabinet and a local exhaust device.SOLUTION: Exposure prevention boxes 10 of this invention are installed in an open-type safety cabinet 100 and an operation room of a local exhaust device to be used. An exposure prevention box forms a hollow box body composed of a bottom wall, a top wall and side walls, and is provided with a container holding part 53 for holding a medicine sealing container on the bottom wall. The bottom wall has an exhaust port 51a communicating with a lower space of the operation room, and the top wall has a filling tool insertion port 63 at a position facing the container holding part.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2019,JPO&INPIT【課題】開放型の安全キャビネットや局所排気装置で抗癌剤や有機溶剤等を調製する際に、作業者が誤ってシリンジの針で手を刺したり、手袋を薬剤や有機溶剤等で汚したりしない暴露防止箱を提供する。【解決手段】本発明の暴露防止箱10は、開放型の安全キャビネット100や局所排気装置の作業室に設置して用いられる。暴露防止箱は、底壁、天壁、及び側壁からなる中空の箱体をなし、底壁に薬剤密封容器を保持する容器保持部53を備えている。底壁は、作業室の下部空間へ連通する排気口51aを有し、天壁は、容器保持部に対向する位置に充填具挿入口63を有している。【選択図】図1