2,3-dihidro-1H-inden-1-on derivati kot z retinojsko kislino povezani antagonisti osirotelih receptrojev gama (ror gama) za zdravljenje multiple skleroze

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专利权人:

Arrien Pharmaceuticals LLC

发明人:

VANKAYALAPATI Hariprasad,YERRAMREDDY Venkatakrishnareddy

申请号：

SI201431560

公开号：

SI3044223T1

申请日:

2014.08.28

申请国别(地区):

SI

年份:

2020

代理人:

摘要：

The present invention is directed to the synthesis of compounds of formula (I) useful for modulating RORγt/RORγ activity and for treating diseases or conditions mediated by RORγt/RORγ and thus disease states associated with immunopathology of human autoimmune diseases such as Multiple Sclerosis (MS), Rheumatoid Arthritis (RA), Inflammatory Colitis, Psoriasis, COPD, Pain, Obesity, Diabetes, Dyslipidemia, Osteoporosis, Asthma, Neurodegenerative diseases and Cancer.

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