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COMPOSES ET PROCEDES POUR LE TRAITEMENT DE LA DOULEUR ET D'AUTRES MALADIES
专利权人:
AQUILUS PHARMACEUTICALS; INC
发明人:
SUCHOLEIKI, IRVING
申请号:
CA2747957
公开号:
CA2747957C
申请日:
2009.12.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to a compound of formula (II)(see formula II)wherein:each of R1, R2, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15 R16, andR17 isindependently selected from the group consisting of deuterium or hydrogen; andR3 isindependently selected from the group consisting of CD3 or CH3, wherein whenR3 isCH3 then at least one of the groups R1, R2, R4, R5, R6, R7, R8 R9, R10, R11,R12, R13, R14,R15 R16, R17 is deuterium; and R18 is hydrogen. The invention relates to amedicamentfor treating a condition that causes pain, on the basis of said compound. Thetechnicalresult is obtaining new MMP (metalloprotease enzyme) inhibitive compounds,whichexhibit the increased activity, the metabolic stability and or the reducedtoxicity relativeto the currently known MMP inhibitors for the treatment of pain and otherdiseases suchas cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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