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EXPRESSION SIGNATURE IN PERIPHERAL BLOOD FOR DETECTION OF AORTIC ANEURYSM
专利权人:
Yulei WANG
发明人:
Yulei WANG,Catalin Barbacioru,Raymond R. Samaha,John A. Elefteriades
申请号:
US13611240
公开号:
US20130006342A1
申请日:
2012.09.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
We hypothesized that gene expression patterns in peripheral blood cells may correlate with TAA disease status, and carried out a comprehensive gene expression survey on peripheral blood cells obtained from TAA patients and normal individuals. A distinct gene expression profile in peripheral blood cells can classify TAA patients from normal individuals. The genes provided by the present teachings define a set of diagnostic markers, thus providing a blood-based gene expression test to facilitate early detection of TAA disease. Methods of distinguishing ascending from descending TAA are also provided, as are methods of distinguishing familial from sporadic TAA.
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