經取代吡咯并嘧啶化合物、其組合物及其治療方法农业专利-农业学术服务平台

发明人:: CALABRESE, ANDREW ANTONY,卡拉布瑞斯　安德瑞　安东,卡拉布瑞斯　安德瑞　安東,BRANDON, JEFFY,布兰登　杰菲,布蘭登　傑菲,ROBINSON, DALE,罗宾森　戴尔,羅賓森　戴爾,ZHU, DAN,朱丹,HUANG, DEHUA,黄得华,黃得華,ELSNER, JAN,爱尔斯纳　珍,愛爾斯納　珍,BOYLAN, JOHN,柏伊兰　约翰,柏伊蘭　約翰,TE,卡拉布瑞斯安德瑞安东,卡拉布瑞斯安德瑞安東,布兰登杰菲,布蘭登傑菲,罗宾森戴尔,羅賓森戴爾,爱尔斯纳珍,愛爾斯納珍,柏伊兰约翰,柏伊蘭約翰

摘要：: Provided herein are Pyrrolopyrimidine Compounds having the following structure:wherein R1, R2, R3, and L are as defined herein, compositions comprising an effective amount of a Pyrrolopyrimidine Compound, and methods for treating or preventing breast cancer, more particularly triple negative breast cancer, comprising administering an effective amount of such Pyrrolopyrimidine Compounds to a subject in need thereof.本文提供具有以下結構之吡咯并嘧啶化合物：其中R1、R2、R3及L係如本文所定義；包含有效量之吡咯并嘧啶化合物之組合物；及用於治療或預防乳癌、更具體而言三重陰性乳癌之方法，該等方法包含向有需要之個體投與有效量之該等吡咯并嘧啶化合物。