Vítor Manuel DE OLIVEIRA E VASCONCELOS,Lucinda Janete DA SILVA BESSA,Anake KIJJOA,Suradet BUTTACHON,Tida DETHOUP,Paulo Manuel RODRIGUES MARTINS DA COSTA
申请号:
US15739353
公开号:
US20180185370A1
申请日:
2016.06.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure relates to compounds and compositions displaying antibacterial activity, particularly against Gram-positive bacteria. The compounds comprise a class of pyrazinoquinazolinone derivatives, including neofiscalin A and fiscalin C, or pharmaceutically acceptable salts, esters, solvates or prodrugs thereof. The present disclosure further relates to methods for treating a patient with a bacterial infection with the disclosed compounds and compositions.