LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR UCLA MEDICAL CENTER
发明人:
FU YUE,EDWARDS JOHN E.,IBRAHIM ASHRAF S.,SPELLBERG BRAD J.
申请号：
CL2011002284
公开号：
CL2011002284A1
申请日:
2011.09.15
申请国别(地区):
CL
年份:
2012
代理人:
摘要：
The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include vaccine compositions having an FTR polypeptide or an antigenic fragment of the polypeptide； a vector including a nucleotide sequence that is substantially complimentary to at least 18 contiguous nucleotides of FTR sequence； an antisense； a small interfering RNA or an antibody inhibitor of FTR. The vaccine compositions of the invention can further include an adjuvant.COMPOSICION DE VACUNA QUE COMPRENDE UN POLIPEPTIDO DE PERMEASA DE HIERRO DE ALTA AFINIDAD (FTR)； Y SU USO PARA TRATAR O PREVENIR UNA CONDICION FUNGICA.
