Daniel Lee Rathbone,Tony Worthington,Sahar Al-Malaika,Matthew Justin Hird,Alexandria Rose Quayle
申请号:
US16725890
公开号:
US20200131223A1
申请日:
2019.12.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to compounds, compositions and polymers comprising a first component adapted to promote germination of Clostridium difficile (C. diff) and a second component which acts as an antimicrobial agent. Said compounds, compositions and polymers are useful for destroying C. diff where conventional antimicrobial agents are unsuccessful. The compositions can be formulated as coating or materials which actively destroy C. diff which come into contact with it. The germination promotion is induced by bile salts. The invention also relates to the use of such materials as a treatment for C. diff associated diseases and toxic megacolon.