PROBLEM TO BE SOLVED: To provide a pharmaceutical composition which binds a polymer which is bond with a HSP inhibitor which improves the drug efficacy of HSP90 (heat shock protein 90) inhibitor and reduces toxicity to normal cells, with an antibody or antibody fragment which specifically binds to HER2 which is the client protein of HSP90.SOLUTION: The invention provides a high molecular compound represented by formula (1) or a salt thereof, and a pharmaceutical composition comprising the same. The HSP90 inhibitor is a resorcinol derivative.COPYRIGHT: (C)2015,JPO&INPIT【課題】HSP90(熱ショック蛋白質90)阻害剤の薬効の向上及び正常細胞に対する毒性の低減させるHSP阻害剤が結合したポリマーとHSP90のクライアント蛋白質であるHER2と特異的に結合する抗体又は抗体断片とを結合させる医薬組成物の提供。【解決手段】式(1)で表される高分子化合物又はその塩、及びそれを含む医薬組成物。前記HSP90阻害剤は、レゾルシノール誘導体である。【選択図】なし
