PROCESS TO PRODUCE 4-HYDROXY-2-OXO-PYRANE DERIVATIVES USEFUL AS PROTEASE INHIBITORS

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专利权人:

PHARMACIA & UPJOHN CO.; KALAMAZOO

发明人:

GAGE, JAMES R.,KELLY, ROBERT C.,HEWITT, BRADLEY D.

申请号：

HU0003593

公开号：

HU228986B1

申请日:

1998.09.03

申请国别(地区):

HU

年份:

2013

代理人:

摘要：

Disclosed is a novel process and novel intermediates to prepare [R-(R*,R*)]-N-[3-[1-[5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide (XIX) which is a protease inhibitor useful in treating humans infected with the HIV virus.

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