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PSMA-TARGETING IMAGING AGENTS
专利权人:
发明人:
Steve Shih-Lin Huang,Warren D. Heston,Xinning Wang
申请号:
US14605124
公开号:
US20150209453A1
申请日:
2015.01.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A PSMA-specific imaging agent comprising a compound according to formula I:are described, wherein S1 is an organic spacer group having from 5 to 30 carbons, A is an amino acid forming a portion of a negatively charged peptide oligomer, n is from 3 to 6, S2 is an organic spacer group having from 5 to 15 carbons, and I is an imaging group, and pharmaceutically acceptable salts thereof. The PSMA-specific imaging agents can be used to image PSMA within a tissue region to guide the treatment of diseases such as prostate cancer.
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