Devices for implanting cells in a host body are described. The device comprises a porous scaffold comprising at least one chamber having a proximal end and a distal end, pores sized to facilitate growth of vascular and connective tissues into the at least one chamber and a polypropylene mesh. A portion of the porous scaffold is coated with one or more materials that stimulates tissue incorporation and angiogenesis. A further device comprises a porous scaffold comprising at least one chamber having a proximal end and a distal end, pores sized to facilitate growth of vascular and connective tissues into the at least one chamber, at least one removable plug configured to be positioned within the at least one chamber and a polypropylene mesh. Comprised with the chamber are stem cells which are immature, partially differentiated, or fully differentiated.