METHODES POUR TRAITER LA DOULEUR CHRONIQUE OU REFRACTAIRE ET/OU POUR AUGMENTER LE SEUIL DE LA DOULEUR CHEZ UN SUJET, ET COMPOSITIONS PHARMACEUTIQUES ASSOCIEES
Methods are provided for reducing chronic inflammatory pain, increasing the levels of endogenous opioid peptides, as well as increasing the pain threshold of a subject having symptoms of androgen deficiency, comprising transdermally administering a composition comprising a bioactive androgen on a daily basis. In addition, the invention also relates to increasing the levels of endogenous opioid peptides in a human subject by administering an androgen composition to the subject. The invention also encompasses administration of a composition consisting essentially of an androgen for the treatment of chronic inflammatory pain, and for increasing the pain-threshold in a subject.
