A composition for topical application with antifungal activity, containing Melaleuca alternifolia essential oil, oregano essential oil, lime essential oil and an ester of vitamin E, that can be, for example, vitamin E acetate, n- propionate or linoleate, and is preferably alpha-tocopheryl acetate; preferably, these oils constitute at least 3% by weight of the composition and each of them constitutes at least 1% by weight of the composition; preferably, the composition contains from 10% to 97% of said ester of vitamin E and can consist of the three aforementioned essential oils and the vitamin E ester; alternatively, the composition can be in the form of hydrophobic gel, containing 10 to 50% of the ester of vitamin E, 20 to 60% of a vegetable butter or wax, from 10 to 30% of triglyceride of caprylic and capric acid and from 5 to 20% of a gelling agent for lipids and at least 3% of the aforementioned essential oils, each of which constitutes at least 1% by weight of the composition.