ПАЛАСИОС ИСКЬЕРДО Беатрис (ES),ВАН ХОГЕВЕСТ Петер (CH),Л. С. ЛИ Мэтью (CH)
申请号：
RU2013134249/15
公开号：
RU2013134249A
申请日:
2011.12.22
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A composition comprising: a) at least a compound of formula (I): wherein Q is a conjugate base of a pharmaceutically suitable organic or inorganic acid, R and R'are independently selected from hydrogen and substituted or unsubstituted C1-6 alkyl, R and R'are independently selected from substituted or unsubstituted aryl radicals, R and R ′ are independently selected from hydrogen, halogen, —CF, —OH, —NH, —O — C 1 -alkyl and substituted or unsubstituted C 1 -Cyl, or R 1 and R 2 together with R 1 and R 2 form respectively substituted and independently unsubstituted radical l -CH = CH-CH = CH, R and R'are independently selected from hydrogen, halogen, -CF, -OH, -NH, -O-C1-6 alkyl and substituted or unsubstituted C1-6 alkyl, or R and R'are compatible with R and R'respectively and independently from each other form a substituted or unsubstituted radical -CH = CH-CH = CH-, m is from 0 to 1, n is an integer selected from 0, 1, 2, 3,4, 5, 6, 7, 8, 9 and 10, p is from 0 to 1, provided that m, n and p are not equal to zero at the same time, or its solvate, and b) at least cyclodextrin or liposome. 2. A composition according to claim 1, wherein R and R are independently selected from substituted or unsubstituted C1-6 alkyl. A composition according to claim 1, wherein R and R are independently selected from Caryl, optionally substituted with halogen. A composition according to claim 1, wherein R and R ′ are methyl, and R and R ′ are independently selected from phenyl optionally substituted with halogen. The composition of claim 1, wherein R and R and R'and R'are independently selected from hydrogen, or R and R'together with R and R'are respectively and independently form the radical -CH = CH-CH = CH-, optionally substituted with halogen. 6. The composition of claim 1, wherein the compound of formula (I) contains the following substituents: 7. The composition of claim 6, wherein the compound of formula (I) is1. Композиция, содержащая:a) по меньшей мере соединение формулы (I):г
