PIPERAZINE AND [1,4] DIAZEPAM DERIVATIVES AS NK ANTAGONISTS

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

HENNER KNUST,MATTHIAS NETTEKOVEN,HASANE RATNI,XIHAN WU

申请号：

BRPI0814253

公开号：

BRPI0814253A2

申请日:

2008.06.04

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention relates to a compound of formula I wherein R1, R2, R3, R4, R9, R10, m and n are as defined herein, or to a pharmaceutically acceptable acid addition salt thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, bipolar disorders, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

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