EDCON CHANG,MICHAEL B. WALLACE,WOLFGANG REINHARD LUDWIG NOTZ
申请号：
BR112015000386
公开号：
BR112015000386A2
申请日:
2013.07.08
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract disclosed are compounds of formula 1, and pharmaceutically acceptable salts thereof, wherein r1, r2, r3, r4, r5, r6, r7, r8, r9, and r10 are defined in the specification. this disclosure also relates to materials and methods for preparing compounds of formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with pi3kd. p3kd-5004-wo translation of the abstract summary "azaindole derivatives which act as pi3k inhibitors" are disclosed compounds of formula 1, and pharmaceutically acceptable salts thereof, wherein r1, r2, r3, r4, r5, r6, r7, r8, r9 and r10 are defined in the descriptive report. This disclosure also relates to materials and methods for preparing compounds of formula 1, pharmaceutical compositions which contain them and their use to treat immune disorders, cardiovascular disease, cancer and other diseases, disorders or conditions associated with pi3kd.abstract disclosed are compounds of formula 1, , and pharmaceutically acceptable salts thereof, wherein r1, r2, r3, r4, r5, r6, r7, r8, r9, and r10 are defined in the specification. this disclosure also relates to materials and methods for preparing compounds of formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with pi3kd. p3kd-5004-wo tradução do resumo resumo "derivados de azaindol os quais agem como inibidores de pi3k" são divulgados compostos de fórmula 1, , e sais farmaceuticamente aceitáveis dos mesmos, em que r1, r2, r3, r4, r5, r6, r7, r8, r9 e r10 são definidos no relatório descritivo. esta divulgação também se refere a materiais e métodos para preparar compostos de fórmula 1, a composições farmacêuticas as quais os contêm e a seu uso para tratar distúrbios imunológicos, doença cardiovascular, c
