Toll like receptor (TLR) stimulation for ocular angiogenesis and macular degeneration

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专利权人:

Jayakrishna Ambati

发明人:

Jayakrishna Ambati

申请号：

US12304450

公开号：

US08957035B2

申请日:

2007.05.15

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of stimulators of the TLR3 and TLR7 receptors, Trif or of IL-10 and IL-12 inhibits ocular angiogenesis. Furthermore, all siRNAs (both targeted and non-targeted) can inhibit ocular angiogenesis.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/