The present invention provides 4-isopropylphenyl glucitol compounds which have no tendency to accumulate in the body and which inhibit SGLT1 activity to suppress postprandial hyperglycemia (or impaired glucose tolerance) through suppression of glucose absorption in the small intestine, whereby the compounds, for example, can suppress the onset of diabetes and metabolic syndrome or can treat these diseases.A 4-isopropylphenyl glucitol compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:wherein R1represents a hydrogen atom, etc., R2represents a methyl group, etc., R3represents a C1-4alkyl group substituted with an amino group(s), etc., and R4represents a hydrogen atom, etc.本發明提供4-異丙基苯基葡萄糖醇化合物，其不具有累積於體內之傾向，且其抑制SGLT1活性以經由抑制小腸中葡萄糖之吸收壓抑餐後血糖過高(或葡萄糖耐受性不良)，該等化合物因此可例如壓抑糖尿病及代謝症候群之發病或可治療此等疾病。一種由下式(I)表示之4-異丙基苯基葡萄糖醇化合物或其醫藥上可接受之鹽：其中R1係表示氫原子等，R2係表示甲基等，R3係表示經胺基取代之C1-4烷基等，且R4係表示氫原子等。
