595291 Discloses an immunogenic composition comprising a conjugated pneumococcal capsular saccharide and two different meningococcal factor H binding protein (fHBP) polypeptides, wherein the fHBP polypeptides are not in the form of meningococcal outer membrane vesicles (OMVs). A method using the composition to raise immune responses against both N. meningitidis and S. pneumonia and processes for preparing the immunogenic composition.