divalent hydrazia compound conjugates to inhibit cystic fibrosis transmembrane conductance regulator

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专利权人:

The Regents Of The University Of California

发明人:

Alan S. Verkman,Nitin D. Sonawane

申请号：

BRPI0910416

公开号：

BRPI0910416A2

申请日:

2009.04.03

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

Provided herein are divalent hydrazide-polyethylene glycol conjugates that inhibit the ion transport activity of a cystic fibrosis transmembrane conductance regulator (CFTR). The conjugates described herein are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased CFTR activity, for example, secretory diarrhea.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/