William A. Carroll;Tongmei Li;Gavin Hirst;Sridhar Peddi;Biqin C. Li;Derek W. Nelson;Eric M. Bunnelle;Arturo Perez-Medrano;Alan S. Florjancic
发明人:
William A. Carroll,Arturo Perez-Medrano,Alan S. Florjancic,Derek W. Nelson,Sridhar Peddi,Tongmei Li,Eric M. Bunnelle,Gavin Hirst,Biqin C. Li
申请号:
US11120718
公开号:
US08217067B2
申请日:
2005.04.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound having Formula (I) or Formula (II)is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.