MAURER LAURA E,PARGAONKAR NIKHIL,MAO CHEN,MA SARINA GRACE HARRIS
申请号:
NZ60174710
公开号:
NZ601747A
申请日:
2010.11.08
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
The disclosure relates to a pharmaceutical compositions and oral dosage forms comprising granules, wherein the granules are prepared using high shear wet granulation and comprise: anhydrous (2R)-2-phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and a C6-18 alkylsulfate or pharmaceutically acceptable salt thereof, preferably sodium lauryl sulphate. These pharmaceutical compositions or oral dosage forms are suitable for treating a disease chosen from schizophrenia, a cognitive impairment disorder, restless legs syndrome, a periodic limb movement disorder, tardive dyskinesia, Huntington&rsquos disease, Parkinson&rsquos disease, hypertension, and excessive daytime sleepiness.