SYSTEM AND METHOD FOR INSULIN-MIMETIC OF CARTILAGE, BONE, OR OSTEOCHONDRAL REPAIR AND PIEZOELECTRIC COMPOSITE SCAFFOLD

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专利权人:

New Jersey Institute of Technology

发明人:

Treena Lynne Arinzeh,Ateka Khader

申请号：

US15722299

公开号：

US20180092943A1

申请日:

2017.10.02

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Shown and described is an insulin-mimetic as an inductive agent for cartilage and/or bone repair is disclosed. Sodium tungstate (Na2WO4) was utilized as an inductive factor to enhance human mesenchymal stem cell (MSC) chondrogenesis. The chondrogenic differentiation of MSCs was enhanced in the presence of low concentrations of Na2WO4 as compared to control, without Na2WO4. Also disclosed is a composite scaffold capable of supporting cell and tissue growth. The composite scaffold could include zinc oxide and polycaprolactone.

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