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POLY((LACTIC-CO-GLYCOLIC ACID)-B-LYSINE) AND PROCESS FOR SYNTHESIZING A BLOCK COPOLYMER OF PLGA AND PLL (POLY-E-CBZ-L-LYSINE)
专利权人:
John Harvey;Daniel Siegwart;Heng Huang;Brian Hess;Alex Aimetti
发明人:
John Harvey,Daniel Siegwart,Heng Huang,Brian Hess,Alex Aimetti
申请号:
US14232525
公开号:
US20150166786A1
申请日:
2012.07.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of synthesizing copolymers is provided. The method can include coupling a degradable polymer to a poly(amino acid) and then deprotecting the copolymer if the poly(amino acid) contains protected side chains. Copolymer compositions are provided. These compositions include PLGA-PLL copolymers, PLGA-PLL-cbz copolymers, and copolymers of a polyester with a carboxylic acid end group coupled to a poly(amino acid) with an amine group. The compositions may include therapeutic blends and formulations of copolymers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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