John Harvey;Daniel Siegwart;Heng Huang;Brian Hess;Alex Aimetti
发明人:
John Harvey,Daniel Siegwart,Heng Huang,Brian Hess,Alex Aimetti
申请号:
US14232525
公开号:
US20150166786A1
申请日:
2012.07.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of synthesizing copolymers is provided. The method can include coupling a degradable polymer to a poly(amino acid) and then deprotecting the copolymer if the poly(amino acid) contains protected side chains. Copolymer compositions are provided. These compositions include PLGA-PLL copolymers, PLGA-PLL-cbz copolymers, and copolymers of a polyester with a carboxylic acid end group coupled to a poly(amino acid) with an amine group. The compositions may include therapeutic blends and formulations of copolymers.