Juan Antonio Diaz Martin;Maria Dolores Jimenez Bargueno
发明人:
Juan Antonio Diaz Martin,Maria Dolores Jimenez Bargueno
申请号：
US12901063
公开号：
US08273733B2
申请日:
2010.10.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The disclosure relates to tetrahydroisoquinoline sulfonamide compounds of formula I:wherein R1, R2, n and B are as defined in the disclosure, their preparation and their use in therapies for the treatment of central nervous system diseases such as vigilance and sleep disorders, narcolepsy, Alzheimer's disease and other dementias, Parkinson's disease, attention disorders in hyperkinetic children, memory and learning disorders, epilepsy, schizophrenia, moderate cognitive disorders, depression, anxiety, sexual dysfunction, dizziness and travel sickness.
